Document Detail

Cytologic detection of human papillomavirus infection.
MedLine Citation:
PMID:  2829079     Owner:  NLM     Status:  MEDLINE    
In recent years there has been a dramatic increase in the incidence of human papillomavirus infection of the female genital tract. Since the primary diagnosis of this condition is almost invariably based on cytologic observations, the diagnostic criteria are of paramount importance. The diagnosis is usually based on the presence of koilocytes, or balloon cells, and dyskeratotic cells. Although these cells remain fundamental to the diagnosis, it is important to recognize other possible cytologic manifestations of the disease. Follow-up studies indicate clearly that any woman with cytologic evidence of HPV infection has a greatly increased risk of developing cervical intraepithelial neoplasia. Morphologic attempts to quantify this risk are unreliable. The studies described and quoted in this paper would suggest that all women with the cytologic changes of HPV infection, with or without evidence of cervical intraepithelial neoplasia, should be managed with extreme caution.
M Drake; G Medley; H Mitchell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology clinics of North America     Volume:  14     ISSN:  0889-8545     ISO Abbreviation:  Obstet. Gynecol. Clin. North Am.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1988-03-23     Completed Date:  1988-03-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8709551     Medline TA:  Obstet Gynecol Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  431-50     Citation Subset:  IM    
Department of Cytopathology, Prince Henry's Hospital, Melbourne, Australia.
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MeSH Terms
Cervix Uteri / cytology*
Follow-Up Studies
Genital Neoplasms, Female / pathology*
Tumor Virus Infections / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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