| Cytokines and myocardial dysfunction: state of the art. | |
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MedLine Citation:
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PMID: 18226775 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Myocardial dysfunction has been associated with inflammation and cytokine modulation. OBJECTIVES: The study objective was to understand the role of cytokines in the pathophysiology and management of myocardial dysfunction. METHODS: Heart failure has been revisited with revision of the pertinent published articles in the Medline, Scopus, Cochrane Database of Systematic Reviews, and EBSCO Host research. RESULTS: For the proinflammatory cytokines, illumination of this important point requires further diagnostic and therapeutic investigations. Data on chronic heart failure are not so reassuring; therefore, patients with advanced heart failure should not be treated with anticytokines at this time. CONCLUSION: Further studies are warranted to pave the way for introducing cytokine and immunomodulation therapy at the optimal and appropriate time. |
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Authors:
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Ayman A El-Menyar |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of cardiac failure Volume: 14 ISSN: 1532-8414 ISO Abbreviation: J. Card. Fail. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-29 Completed Date: 2008-02-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9442138 Medline TA: J Card Fail Country: United States |
Other Details:
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Languages: eng Pagination: 61-74 Citation Subset: IM |
Affiliation:
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Weill Cornell Faculty of Medicine, Doha, Qatar. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Cardiomyopathies / drug therapy*, mortality, physiopathology* Cardiotonic Agents / therapeutic use* Cytokines / blood* Female Heart Failure / drug therapy*, mortality, physiopathology* Humans Interleukin-10 / blood Interleukin-6 / blood Male Prognosis Randomized Controlled Trials as Topic Sensitivity and Specificity Severity of Illness Index Survival Analysis Treatment Outcome Tumor Necrosis Factor-alpha / blood |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Cardiotonic Agents; 0/Cytokines; 0/Interleukin-6; 0/Tumor Necrosis Factor-alpha; 130068-27-8/Interleukin-10 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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