| Cytokines and matrix metalloproteinases mRNA expression in archival human tissues from failed total hip arthroplasty using in situ hybridization and color video image analysis. | |
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MedLine Citation:
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PMID: 9553699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reports on the histological and biochemical nature of periprosthetic fibrous/granulomatous tissue has, to date, been largely limited to frozen tissue sections. This study reports the cytokine and matrix metalloproteinase profiles found in periprosthetic interface tissues in THA which have failed due to aseptic loosening and in capsular tissues obtained at primary surgery. The study employs immunohistochemistry, in situ hybridization, and color video image analysis on formalin fixed and paraffin embedded sections. |
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Authors:
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Y Yu; W R Walsh; D H Sonnabend; J L Yang; F Bonar; B Markovic; W Bruce; L Kohan; M Neil |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin (Hospital for Joint Diseases (New York, N.Y.)) Volume: 57 ISSN: 0018-5647 ISO Abbreviation: Bull Hosp Jt Dis Publication Date: 1998 |
Date Detail:
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Created Date: 1998-07-08 Completed Date: 1998-07-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9215948 Medline TA: Bull Hosp Jt Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 23-9 Citation Subset: IM |
Affiliation:
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Orthopaedic Research Laboratory, Prince of Wales Hospital, University of New South Wales, Sydney, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Arthroplasty, Replacement, Hip* Cytokines / analysis* DNA Probes Enzyme Induction Female Granulation Tissue / chemistry* Humans Immunohistochemistry In Situ Hybridization Male Matrix Metalloproteinase 3 / analysis* Middle Aged Osteoarthritis / surgery Prosthesis Failure* RNA, Messenger / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 0/DNA Probes; 0/RNA, Messenger; EC 3.4.24.17/Matrix Metalloproteinase 3 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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