| Cytokine profiles before and after exchange transfusion in a neonate with transient myeloproliferative disorder and hepatic fibrosis. | |
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MedLine Citation:
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PMID: 20445414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To study the effect of exchange transfusion on cytokine profiles in a patient with transient myeloproliferative disorder and hepatic fibrosis in which cytokines were measured before and after exchange transfusion. A newborn female was diagnosed with Down syndrome phenotypically and on karyotyping. Laboratory data showed a high leukocyte count with blast cells in the peripheral blood and liver dysfunction. Exchange transfusion was performed on day 1. However, respiratory distress and multiorgan failure progressed, and she died after 16 days. Of the cytokines examined, transforming growth factor-beta1 and interleukin-7 were extremely high before exchange transfusion, and decreased after exchange transfusion. |
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Authors:
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Tokio Sugiura; Kenji Goto; Takeshi Ninchoji; Kaori Aiba; Masanori Kouwaki; Norihisa Koyama; Hajime Togari |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 32 ISSN: 1536-3678 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-06 Completed Date: 2010-05-27 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: e164-6 Citation Subset: IM |
Affiliation:
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Department of Pediatrics and Neonatology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. sugitoki23@yahoo.co.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Down Syndrome
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metabolism* Exchange Transfusion, Whole Blood* Fatal Outcome Female Humans Infant, Newborn Interleukin-7 / metabolism* Liver Cirrhosis / metabolism*, therapy Myeloproliferative Disorders / metabolism*, therapy Transforming Growth Factor beta1 / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Interleukin-7; 0/Transforming Growth Factor beta1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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