Document Detail


Cytogenetic studies on the nucleolar organizer region [NOR] activity in meningioma cells with normal and hypodiploid karyotypes.
MedLine Citation:
PMID:  7104986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association pattern and NOR silver staining of the acrocentric chromosomes was studied in normal and hypodiploid cell lines of four meningioma patients. In three cases the hypodiploid cells showed a more increased association frequency or NOR silver staining or both than the normal ones, indicating a compensatory mechanism between the NORs. Chromosomes #14 seemed to be more frequently involved in this phenomenon than other acrocentric chromosomes. From the silver staining results it was concluded that in meningioma cells, chromosomes #22 which bear active as well as inactive NORs were missing. The compensation between the NORs was probably only activated if an active NOR was lost.
Authors:
H Zankl; H Huwer; K D Zang
Related Documents :
15468956 - Atomic force microscopy of human metaphase chromosomes after differential staining of s...
18469986 - In situ nick translation of meiotic chromosomes to demonstrate homologous heterochromat...
3530406 - The influence of fixation on the morphology of mitotic chromosomes.
2253276 - Electrophoretic karyotyping without the need for generating protoplasts.
12209816 - Integrated bioprocessing in saccharomyces cerevisiae using green fluorescent protein as...
7727766 - Frequent deletion of p16ink4a/mts1 and p15ink4b/mts2 in pediatric acute lymphoblastic l...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  6     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-10-29     Completed Date:  1982-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  47-53     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cell Line
Chromosome Deletion
Chromosomes, Human, 13-15
Chromosomes, Human, 21-22 and Y
Diploidy
Humans
Meningeal Neoplasms / genetics*
Meningioma / genetics*
Nucleolus Organizer Region / ultrastructure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Retinoblastoma and its association with a deletion in chromosome #13: a survey using high-resolution...
Next Document:  Genetic/epidemiological findings in a study of smoking-associated tumors.