Document Detail

Cytogenetic studies in male infertility: a review.
MedLine Citation:
PMID:  2056021     Owner:  NLM     Status:  MEDLINE    
Among those factors known to influence spermatogenesis, chromosomal aberration is perhaps the best known. A review of the literature on mitotic studies in infertile men showed that 12% of the azoospermic and severe oligozoospermic (sperm count less than 10 x 10(6)/ml) males had a karyotypic abnormality; they mainly consisted of an XXY constitution or a Robertsonian or reciprocal translocation. A similar review on meiotic studies revealed that 8% of the infertile males had some kind of cytogenetic error. Therefore, mitotic and meiotic studies are indicated in males with severe gamete impairment when the other possible causes have been eliminated.
M De Braekeleer; T N Dao
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  6     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-07-31     Completed Date:  1991-07-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  245-50     Citation Subset:  IM    
Group in Human Genetics, SOREP, Université du Quebec à Chicoutimi, Canada.
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MeSH Terms
Chromosome Aberrations / genetics*
Chromosome Disorders
Infertility, Male / genetics*
Meiosis / genetics*
Mitosis / genetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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