Document Detail


Cytogenetic studies in male infertility: a review.
MedLine Citation:
PMID:  2056021     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Among those factors known to influence spermatogenesis, chromosomal aberration is perhaps the best known. A review of the literature on mitotic studies in infertile men showed that 12% of the azoospermic and severe oligozoospermic (sperm count less than 10 x 10(6)/ml) males had a karyotypic abnormality; they mainly consisted of an XXY constitution or a Robertsonian or reciprocal translocation. A similar review on meiotic studies revealed that 8% of the infertile males had some kind of cytogenetic error. Therefore, mitotic and meiotic studies are indicated in males with severe gamete impairment when the other possible causes have been eliminated.
Authors:
M De Braekeleer; T N Dao
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  6     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-07-31     Completed Date:  1991-07-31     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  245-50     Citation Subset:  IM    
Affiliation:
Group in Human Genetics, SOREP, Université du Quebec à Chicoutimi, Canada.
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MeSH Terms
Descriptor/Qualifier:
Chromosome Aberrations / genetics*
Chromosome Disorders
Humans
Infertility, Male / genetics*
Karyotyping
Male
Meiosis / genetics*
Mitosis / genetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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