| Cytodiagnosis of secretory carcinoma of the breast: a report on two cases. | |
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MedLine Citation:
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PMID: 21104739 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Secretory carcinoma of the breast is a rare (<1%) low grade breast carcinoma which shows distinct features at histology. Diagnosis of this carcinoma at fine needle aspiration cytology (FNAC) is difficult. Two cases of secretory carcinoma of the breast presenting as a breast mass, one in a 24-year-old female and the other in a 40-year-old female are reported, highlighting their appearance at FNAC. In both the cases the aspirates were cellular and consisted of clusters and single cells with uniform round nuclei showing minimal nuclear atypia. Most of the cells had moderate to abundant cytoplasm with prominent intracytoplasmic vacuoles. Many cells showed a plasmacytoid appearance and others were binucleate. A typical amphophilic bubbly cytoplasm of the tumor cells was observed. Both cases were confirmed as secretory carcinoma on histology. The differences in cell morphology at FNAC of secretory carcinoma of the breast from other breast carcinomas, and its utility of making a preoperative diagnosis are discussed. |
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Authors:
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Madhusmita Jena; Shameem Shariff |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diagnostic cytopathology Volume: 38 ISSN: 1097-0339 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2011-03-02 Revised Date: 2011-12-06 |
Medline Journal Info:
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Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: United States |
Other Details:
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Languages: eng Pagination: 921-4 Citation Subset: IM |
Copyright Information:
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© 2010 Wiley-Liss, Inc. |
Affiliation:
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Department of Pathology, MVJ Medical College and Research Hospital, Bangalore 562114, Karnataka, India. jena_madhusmita@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy, Fine-Needle Breast / pathology Breast Neoplasms* / diagnosis, pathology Carcinoma* / diagnosis, pathology Cytodiagnosis Cytoplasm / pathology Female Humans Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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