Document Detail

Cytochemical identification of secreted carbohydrates in the endolymphatic sac.
MedLine Citation:
PMID:  3207008     Owner:  NLM     Status:  MEDLINE    
Carbohydrate complexes were investigated in the murine endolymphatic sac by means of histochemical techniques in normal untreated animals as well as after ethacrynic acid treatment. The light epithelial cells were classified into three different types: normal, granular and vacuolar. The granular and vacuolar cells were believed to secrete glycoproteins and/or proteoglycans, the presence of which was closely correlated with the component of the precipitate in the lumen of the endolymphatic sac. This finding suggested that the light cells not only absorb endolymph but may also be involved with secretory activity. Such a dual modality in function may have several important implications, since it suggests that the endolymphatic sac has both absorptive and secretory functions.
M Takumida; D Bagger-Sjöbäck; H Rask-Andersen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  106     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:    1988 Nov-Dec
Date Detail:
Created Date:  1989-02-07     Completed Date:  1989-02-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  417-27     Citation Subset:  IM    
Department of Otolaryngology, Karolinska Sjukhuset, Stockholm, Sweden.
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MeSH Terms
Ear, Inner / metabolism*
Endolymphatic Sac / metabolism*
Ethacrynic Acid / pharmacology
Glycoproteins / metabolism*
Microscopy, Electron
Microscopy, Electron, Scanning
Stimulation, Chemical
Reg. No./Substance:
0/Glycoproteins; 58-54-8/Ethacrynic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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