Document Detail

Cystic tumors of the liver: a practical approach.
MedLine Citation:
PMID:  18595127     Owner:  NLM     Status:  MEDLINE    
Biliary cyst tumors (cystadenoma and cystadeno-carcinoma) are an indication for liver resection. They account for only 5% of all solitary cystic lesions of the liver, but differential diagnosis with multiloculated or complicated biliary cysts, atypical hemangiomas, hamartomas and lymphangiomas may be difficult. The most frequent challenge is to differentiate biliary cyst tumors from hemorrhagic cysts. Computerized tomography (CT) and magnetic resonance imaging (MRI) are often not diagnostic and in these cases fine needle aspiration (FNA) is used to confirm the presence of atypical biliary cells. FNA, however, lacks adequate sensitivity and specificity and should always be used in conjunction with imaging. Pre-operative differentiation of cystadenoma from cystadenocarcinoma is impossible and surgery must be performed if a biliary cyst tumor is suspected. When multiple cystic lesions are observed throughout the liver parenchyma, it is important to exclude liver metastasis, of which colonic cancer is the most common primary site. Multiple biliary hamartomas (von Meyenburg complex) can appear as a mixture of solid and cystic lesions and can be confused with cystic metastasis. Strong and uniform T2 hyperintensity on MRI is usually diagnostic, but occasionally a percutaneous biopsy may be required.
Paolo Del Poggio; Marco Buonocore
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  14     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-07-02     Completed Date:  2008-10-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  3616-20     Citation Subset:  IM    
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MeSH Terms
Bile Duct Neoplasms / pathology*,  surgery
Bile Ducts, Intrahepatic / pathology*,  surgery
Biliary Tract Surgical Procedures
Biopsy, Fine-Needle
Cystadenocarcinoma / pathology*,  surgery
Cystadenoma / pathology*,  surgery
Cysts / pathology*
Diagnosis, Differential
Liver Diseases / pathology*
Liver Neoplasms / secondary*
Magnetic Resonance Imaging
Neoplasm Invasiveness
Predictive Value of Tests
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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