Document Detail

Cystic leukomalacia in the cerebellar folia of premature infants.
MedLine Citation:
PMID:  8546030     Owner:  NLM     Status:  MEDLINE    
Cystic necrosis in the cerebellar white matter was found in three premature infants. The necrosis was characteristically localized in the center of the white matter of the superficial cerebellar folia, sparing the overlying cortex. The patients were aged between 28 and 34 gestational weeks, and had a clinical history of severe systemic hypotension. Thus, cystic leukomalacia represents a characteristic brain lesion in premature infants which may be caused by cerebellar hypoperfusion.
A Tsuru; M Mizuguchi; S Takashima
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neuropathologica     Volume:  90     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1995  
Date Detail:
Created Date:  1996-02-13     Completed Date:  1996-02-13     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  400-2     Citation Subset:  IM    
Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, Tokyo, Japan.
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MeSH Terms
Brain / pathology
Cerebellar Diseases / congenital,  metabolism,  pathology*
Cerebellum / metabolism,  pathology*
Glial Fibrillary Acidic Protein / metabolism
Hypoxia, Brain / pathology
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / metabolism,  pathology*
Reg. No./Substance:
0/Glial Fibrillary Acidic Protein

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