Document Detail

Cystic fibrosis in blacks in Washington, DC: fifteen years' experience.
MedLine Citation:
PMID:  2709429     Owner:  NLM     Status:  MEDLINE    
Controversies exist regarding the clinical presentation and characteristics of cystic fibrosis (CF) in American blacks. Between 1971 and 1986, 188 patients with CF (165 whites, 20 blacks, and 3 others) seen at Children's Hospital National Medical Center, Washington, DC, were evaluated for age at diagnosis, duration of symptoms prior to diagnosis, clinical presentations, initial sputum culture results, and weight and height at diagnosis. Comparisons between black and white patients revealed no statistically significant differences in average age at diagnosis, average duration of symptoms prior to diagnosis, average sweat electrolyte concentrations, or sputum culture results. A breakdown of presenting symptoms by race showed some points of disparity. About twice as many black patients as white patients (40% v 22%) presented with only pulmonary symptoms, whereas slightly more whites presented with only gastrointestinal symptoms (46% v 35%). Those patients presenting with a combination of symptomatology were equally distributed by race (25% black, 21% white). At diagnosis, age-adjusted weight percentiles were significantly lower for black patients than for white patients (chi 2 = 9.60, P less than or equal to 0.05). Although the authors agree that CF is relatively rare among blacks, a high index of suspicion is essential for early diagnosis.
N Prapphal; S B Fitzpatrick; P Getson; R Fink; R O'Donnell; H Chaney
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  81     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-05-26     Completed Date:  1989-05-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
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MeSH Terms
African Continental Ancestry Group*
Child, Preschool
Cystic Fibrosis / epidemiology*
District of Columbia
Infant, Newborn
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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