Document Detail

Cystic fibrosis and hemolytic uremic syndrome coexisting during pregnancy.
MedLine Citation:
PMID:  11975963     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: As more women with cystic fibrosis are living into their reproductive years, this disease can complicate pregnancy and coexist with other entities. We report a case of cystic fibrosis with hemolytic uremic syndrome. CASE: An 18-year-old primigravida with cystic fibrosis was admitted at term with pulmonary symptoms, hypertension, and thrombocytopenia. She was delivered with the admitting diagnosis of severe preeclampsia. Postpartum, thrombocytopenia, and microangiopathic hemolytic anemia worsened. She developed renal failure and acute respiratory distress syndrome, requiring plasmapheresis, mechanical ventilation, and hemodialysis. Renal biopsy was consistent with the diagnosis of hemolytic uremic syndrome. CONCLUSION: Cystic fibrosis, a disease once managed predominantly by pediatric subspecialists, will be seen increasingly by physicians caring for adults, including obstetrician-gynecologists. We may also expect to see it coexisting with other disorders. The management of such patients may prove challenging.
Lauren A Plante; Esteban Ortega
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  99     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-04-26     Completed Date:  2002-09-17     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  930-2     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, MCP-Hahnemann University Hospital, Philadelphia, Pennsylvania, USA.
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MeSH Terms
Cystic Fibrosis / complications*
Hemolytic-Uremic Syndrome / complications*,  diagnosis
Pregnancy Complications / diagnosis,  physiopathology*

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