| Cystic fibrosis pulmonary guidelines: pulmonary complications: hemoptysis and pneumothorax. | |
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MedLine Citation:
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PMID: 20675678 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RATIONALE: Cystic fibrosis (CF) is a recessive genetic disease characterized by dehydration of the airway surface liquid and impaired mucociliary clearance. As a result, individuals with the disease have difficulty clearing pathogens from the lung and experience chronic pulmonary infections and inflammation. There may be intermittent pulmonary exacerbations or acute worsening of infection and obstruction, which require more intensive therapies. Hemoptysis and pneumothorax are complications commonly reported in patients with cystic fibrosis. OBJECTIVES: This document presents the CF Foundation's Pulmonary Therapies Committee recommendations for the treatment of hemoptysis and pneumothorax. METHODS: The committee recognized that insufficient data exist to develop evidence-based recommendations and so used the Delphi technique to formalize an expert panel's consensus process and develop explicit care recommendations. MEASUREMENTS AND MAIN RESULTS: The expert panel completed the survey twice, allowing refinement of recommendations. Numeric responses to the questions were summarized and applied to a priori definitions to determine levels of consensus. Recommendations were then developed to practical treatment questions based upon the median scores and the degree of consensus. CONCLUSIONS: These recommendations for the management of the patient with CF with hemoptysis and pneumothorax are designed for general use in most individuals but should be adapted to meet specific needs as determined by the individuals, their families, and their health care providers. It is hoped that the guidelines provided in this manuscript will facilitate the appropriate application of these treatments to improve and extend the lives of all individuals with cystic fibrosis. |
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Authors:
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Patrick A Flume; Peter J Mogayzel; Karen A Robinson; Randall L Rosenblatt; Lynne Quittell; Bruce C Marshall; ; |
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Publication Detail:
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Type: Journal Article; Practice Guideline |
Journal Detail:
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Title: American journal of respiratory and critical care medicine Volume: 182 ISSN: 1535-4970 ISO Abbreviation: Am. J. Respir. Crit. Care Med. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-02 Completed Date: 2010-09-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9421642 Medline TA: Am J Respir Crit Care Med Country: United States |
Other Details:
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Languages: eng Pagination: 298-306 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. flumepa@musc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Aircraft Anti-Bacterial Agents / therapeutic use Anti-Inflammatory Agents, Non-Steroidal / administration & dosage Bronchial Arteries Bronchoscopy Chest Tubes Cystic Fibrosis / complications*, therapy Decision Making Delphi Technique Embolization, Therapeutic Hemoptysis / etiology*, pathology, therapy* Hospitalization Humans Lung / surgery Lung Transplantation Patient Selection Pleurodesis / methods Pneumothorax / etiology*, pathology, therapy* Positive-Pressure Respiration Recurrence / prevention & control Saline Solution, Hypertonic / administration & dosage Severity of Illness Index Spirometry Travel Weight Lifting |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Saline Solution, Hypertonic |
| Investigator | |
Investigator/Affiliation:
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Patrick A Flume / ; Peter Mogayzel / ; James Cunningham / ; Anne Downs / ; Jill Fleige / ; Chris Goss / ; Hector Gutierrez / ; Leslie Hazle / ; Robert Kuhn / ; Mary Lester / ; Bruce Marshall / ; Lynne Quittel / ; Karen A Robinson / ; Randall Rosenblatt / ; Kathryn Sabadosa / ; Robert L Vender / ; Terry B White / ; Donna Beth Willey-Courand / ; Melissa Chin / ; Carlos E Milla / ; Jeff Wagener / ; Christopher M Oermann / ; Thomas Ferkol / ; Wyn Hoover / ; Michelle S Howenstine / ; Michael J Rock / ; George Retsch-Bogart / ; Ronald Rubenstein / ; Michael Schechter / ; David M Orenstein / ; John L Colombo / ; Beryl Rosenstein / ; Henry L Dorkin / ; James D Acton / ; Susanna A McColley / ; Felix Ratjen / ; Moira L Aitken / ; Paul Mohabir / ; Jerry A Nick / ; Marcia Katz / ; Daniel Rosenbluth / ; Randall K Young / ; Aruna Sannut / ; Guillermo A doPico / ; James R Yankaskas / ; Douglas Holsclaw / ; Linda L Wolfenden / ; Joseph M Pilewski / ; Peter J Murphy / ; Michael P Boyle / ; Ahmet Uluer / ; Steven D Strausbaugh / ; Patricia M Joseph / ; Manu Jain / ; Elizabeth Tullis / ; Souheil Saddekni / ; Patricia Burrows / ; Mark Wholey / ; Charles Burke / ; Mark Sands / ; Sally Mitchell / ; R Duane Davis / ; Thomas M Egan / ; Charles B Huddleston / ; Mike Mulligan / ; David McGiffin / ; Wickii Vigneswaran / ; Craig Lillehei / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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