Document Detail


Cylindrical meanderline radiofrequency coil for intravascular magnetic resonance studies of atherosclerotic plaque.
MedLine Citation:
PMID:  15690524     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to improve the performance of magnetic resonance imaging and spectroscopy of atherosclerotic plaque the potential use of novel radiofrequency coil structures with sensitive detection volumes tailored to the geometry of the arterial wall was investigated. It was found that a cylindrical meanderline (zig-zag) coil design provides a sensitive volume that is restricted to a cylindrical shell, thereby maximizing the filling factor and signal-to-noise ratio for plaques while reducing the intense blood signal. The cylindrical meanderline coil has the added advantages of an open interior, which allows for unimpeded blood flow during scanning, and the potential to be expanded against the walls of the artery, thereby stabilizing the coil against the pulsatile blood flow and minimizing motion artifacts. The performance of cylindrical meanderline coils with theoretical simulations of the electromagnetic fields as well as with experimental images of test objects (phantoms) and human endarterectomy surgical specimens is demonstrated. This radically new RF coil geometry offers the potential to improve the efficiency of MR data acquisition in medical applications in which curved surfaces or slabs contain the material of interest.
Authors:
Christian T Farrar; Van J Wedeen; Jerome L Ackerman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  53     ISSN:  0740-3194     ISO Abbreviation:  Magn Reson Med     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-03     Completed Date:  2005-04-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Wiley-Liss, Inc.
Affiliation:
Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.
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MeSH Terms
Descriptor/Qualifier:
Arteriosclerosis / diagnosis*
Blood Vessels / pathology
Equipment Design
Humans
Magnetic Resonance Imaging / instrumentation*,  methods
Phantoms, Imaging
Pulsatile Flow
Radio Waves
Grant Support
ID/Acronym/Agency:
P41RR14075/RR/NCRR NIH HHS; R01MH64004/MH/NIMH NIH HHS; S10RR16811/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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