Document Detail


Cyclotrons and radiopharmaceuticals in positron emission tomography. Council on Scientific Affairs. Report of the Positron Emission Tomography Panel.
MedLine Citation:
PMID:  3278157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positron emission tomography (PET) can probe biochemical pathways in vivo and can provide quantitative data; for that purpose, tracers labeled with positron-emitting radioisotopes are essential. This report describes the tracers that are being used or that may have future use, their production by cyclotrons, and other needed resources for PET imaging. Current routine and automated methods for convenient production of labeled compounds, coupled with simple computer-controlled accelerators, can support the creation of clinical PET centers in any large medical institution, obviating the need for in-depth research teams. An alternate approach involves the development of regional centers that provide in-house service and that supply fluorine 18- and carbon 11-labeled compounds to nearby hospitals with PET machines.
Authors:
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  JAMA : the journal of the American Medical Association     Volume:  259     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-07     Completed Date:  1988-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1854-60     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Brain / radionuclide imaging
Heart / radionuclide imaging
Humans
Neoplasms / radionuclide imaging
Particle Accelerators*
Radioisotopes / diagnostic use*
Radionuclide Generators
Tomography, Emission-Computed / methods*
Chemical
Reg. No./Substance:
0/Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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