Document Detail


Cyclosporine and Lactation: When the Mother Is Willing to Breastfeed.
MedLine Citation:
PMID:  21240055     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We describe a woman treated with cyclosporine after renal transplantation who commenced breastfeeding of her newborn infant. The child had no apparent clinical adverse effects to cyclosporine. To confirm the safety of breastfeeding and guide the patient and her clinician, cyclosporine concentrations in maternal blood, breast milk, and infant blood were measured. Maternal cyclosporine concentration (1-hour postdose) was 49 μg/L, and the breast milk cyclosporine concentration (2-hour postdose) was 46 μg/L. Infant cyclosporine blood concentration shortly after breastfeeding was undetectable (<10 μg/L). Analysis revealed that the estimated infant exposure to cyclosporine via breast milk was minimal and provided reassurance to continue breastfeeding in this case.
Authors:
Alla Osadchy; Gideon Koren
Related Documents :
7369315 - Congenital horizontal tarsal kink.
21481015 - Preterm and term neonates transplacentally acquire igg antibodies specific to lps from ...
25469645 - Perinatal conditions related to growth restriction and inflammation are associated with...
19797845 - Profile and issues of prospective birth cohort in japan.
16078225 - Biology of neuroblastomas that were found by mass screening at 6 months of age in japan.
9480965 - Similar hypoxic ventilatory responses in sea-level natives and high-altitude andean nat...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-13
Journal Detail:
Title:  Therapeutic drug monitoring     Volume:  -     ISSN:  1536-3694     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909660     Medline TA:  Ther Drug Monit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Sagittal Decompensation Following Corrective Osteotomy for Lumbar Degenerative Kyphosis; Classificat...
Next Document:  Urine Analysis of 3,4-Methylenedioxypyrovalerone in Opioid-Dependent Patients by Gas Chromatography-...