Document Detail


Cyclosporin A treatment for membranoproliferative glomerulonephritis type II.
MedLine Citation:
PMID:  12119488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A nephrotic patient with membranoproliferative glomerulonephritis type II (MPGN II) was treated with cyclosporin A (CSA) and alternate-day low-dose prednisolone. This patient developed the nephrotic syndrome twice. The second episode of the nephrotic syndrome was steroid resistant, and therefore this patient was treated with a CSA regimen. During treatments with alternate-day low-dose prednisolone and CSA, this patient recovered from the nephrotic syndrome. We conclude that CSA therapy may be effective for patients with the steroid-resistant nephrotic syndrome caused by MPGN II.
Authors:
Takahiro Kiyomasu; Minoru Shibata; Hideo Kurosu; Kazuhiro Shiraishi; Hisako Hashimoto; Tadashi Hayashidera; Yuichi Akiyama; Nobuaki Takeda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nephron     Volume:  91     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-07-16     Completed Date:  2003-03-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  509-11     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Affiliation:
Department of Pediatrics, Kyoto National Hospital, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan. tkiyomas@kyotolan.hosp.go.jp
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MeSH Terms
Descriptor/Qualifier:
Child
Complement C3 / metabolism
Cyclosporine / therapeutic use*
Glomerular Mesangium / cytology,  pathology
Glomerulonephritis, Membranoproliferative / drug therapy*
Glucocorticoids / therapeutic use
Humans
Immunosuppressive Agents / therapeutic use*
Japan
Male
Prednisolone / therapeutic use
Chemical
Reg. No./Substance:
0/Complement C3; 0/Glucocorticoids; 0/Immunosuppressive Agents; 50-24-8/Prednisolone; 59865-13-3/Cyclosporine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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