Document Detail


Cyclosporin-induced remission in an infant with alkylating agents-resistant nephrotic syndrome. A case report.
MedLine Citation:
PMID:  8560611     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The efficacy of cyclosporin-A, a potent immunosuppressive agent, has not been clearly proven in the management of childhood nephrotic syndrome. The occurrence of early relapse as the dose of cyclosporin is tapered or as soon as the drug is stopped and the potential nephrotoxic effects of prolonged treatment have caused it to be used in limited cases. We report an eighteen-month-old boy with steroid toxicity and alkylating agents-resistant nephrotic syndrome, who subsequently went very quickly into remission lasting at least one year after receiving cyclosporin-A for only three months.
Authors:
G G Yilmaz; A G Güven
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  37     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    1995 Oct-Dec
Date Detail:
Created Date:  1996-02-27     Completed Date:  1996-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  TURKEY    
Other Details:
Languages:  eng     Pagination:  411-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Akdeniz University Faculty of Medicine, Antalya, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Alkylating Agents / therapeutic use*
Cyclosporine / pharmacology,  therapeutic use*
Drug Resistance
Edema / etiology
Humans
Immunosuppressive Agents / therapeutic use*
Infant
Male
Nephrotic Syndrome / complications,  drug therapy*
Proteinuria / etiology
Recurrence
Chemical
Reg. No./Substance:
0/Alkylating Agents; 0/Immunosuppressive Agents; 59865-13-3/Cyclosporine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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