| Cyclosporin A in the treatment of posterior uveitis. | |
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MedLine Citation:
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PMID: 3857775 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cyclosporin A was used in nine patients with severe refractory posterior uveitis. Four patients had Behcet's disease, one had sarcoidosis, one had HLA B27 related arthritis and uveitis and three had idiopathic retinal vasculitis. The drug had beneficial ocular effects in all patients in the early stages of treatment with an improvement in the visual acuity and reduction in the severity of inflammation. The relapse rate and need for additional steroids were reduced in all patients. However, renal function deteriorated in seven patients to such an extent that the dose of Cyclosporin A had to be reduced with consequent relapse of uveitis. |
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Authors:
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E M Graham; M D Sanders; D G James; A Hamblin; E Kasp Grochowska; D Dumonde |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Transactions of the ophthalmological societies of the United Kingdom Volume: 104 ( Pt 2) ISSN: 0078-5334 ISO Abbreviation: Trans Ophthalmol Soc U K Publication Date: 1985 |
Date Detail:
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Created Date: 1985-06-13 Completed Date: 1985-06-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0200570 Medline TA: Trans Ophthalmol Soc U K Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 146-51 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Behcet Syndrome / complications Cyclosporins / therapeutic use* Female Humans Male Middle Aged Retinal Diseases / complications Sarcoidosis / complications Uveitis / complications, drug therapy*, immunology Visual Acuity / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Cyclosporins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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