Document Detail

Cycloplegic and noncycloplegic refractions of Chinese neonatal infants.
MedLine Citation:
PMID:  21087952     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To examine Chinese neonatal infants with both cycloplegic and noncycloplegic retinoscopy and to compare the distribution of refractive errors for the two techniques.
METHODS: Cycloplegic retinoscopy was performed by two experienced pediatric ophthalmologists on 81 neonatal infants randomly selected from a group of 185 neonates who had undergone noncycloplegic retinoscopy. All infants were between 1 day and 6 days of age and were born without incident at full term.
RESULTS: The mean cycloplegic spherical equivalent (CSE) was highly hyperopic (+3.55 diopters [D] ± 2.39 D). The mean noncycloplegic spherical equivalent (nCSE) was +0.58 D ± 2.32 D. The high reliability of the refractive measurements was demonstrated by high correlations between examiners (CSE: OD, r = 0.96; OS, r = 0.97; nCSE: OD, r = 0.94; OS, r = 0.93 OS) and between eyes (CSE: examiner 1, r = 0.94; examiner 2, r = 0.95; nCSE: examiner 1, r = 0.95; examiner 2, r = 0.97). The correlation between CSE and nCSE was much lower (examiner 1: OD, r = 0.76; OS, r = 0.73; examiner 2: OD, r = 0.72; OS, r = 0.70). Prevalence of astigmatism was very low (1.6% ≥ 1.0 D).
CONCLUSIONS: The level of hyperopia was very high in these infants, and the offsetting tonic accommodation demonstrated by the difference between CSE and nCSE was much higher than in any previous report. Low amounts of infantile hyperopia and high astigmatism are associated with future myopia in the West. The Chinese neonates in this study had high amounts of hyperopia and little astigmatism, yet they are at high risk to become myopic.
Jie Chen; Ailan Xie; Lijie Hou; Yanfeng Su; Fan Lu; Frank Thorn
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-04-14
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  52     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-04-15     Completed Date:  2011-06-22     Revised Date:  2013-01-09    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2456-61     Citation Subset:  IM    
School of Optometry and Ophthalmology, Wenzhou Medical College, Wenzhou, China.
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MeSH Terms
Accommodation, Ocular
Asian Continental Ancestry Group
Cyclopentolate / administration & dosage
Drug Combinations
Gestational Age
Infant, Newborn
Mydriatics / administration & dosage*
Phenylephrine / administration & dosage
Pupil / drug effects*
Refraction, Ocular / drug effects*
Refractive Errors / diagnosis*
Reproducibility of Results
Reg. No./Substance:
0/Drug Combinations; 0/Mydriatics; 512-15-2/Cyclopentolate; 59-42-7/Phenylephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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