Document Detail


Cyclophosphamide in the treatment of immune hemocytopenias
MedLine Citation:
PMID:  54306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Personal experiences with the immunosuppressive therapy of immunohaemocytopenia by cyclophosphamide are represented. A significant therapeutic success in autoimmunohaemolytic anaemia could be registered in 22 patients treated from one to seven years. From a number of 11 patients 9 were in complete remission. In idiopathic thrombocytopenia, however, only 7 patients from a number of 10 were in a clinical remission, the number of thrombocytes remained unchanged. The control of the complement content and the component C'3 can be used well as an indicator for immunological defense when the activity of the process and the success of the therapy are to be evaluated.
Authors:
A Sakalová; M Hrubisko
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Folia haematologica (Leipzig, Germany : 1928)     Volume:  102     ISSN:  0323-4347     ISO Abbreviation:  Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch.     Publication Date:  1975  
Date Detail:
Created Date:  1976-03-30     Completed Date:  1976-03-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374615     Medline TA:  Folia Haematol Int Mag Klin Morphol Blutforsch     Country:  GERMANY, EAST    
Other Details:
Languages:  ger     Pagination:  559-64     Citation Subset:  IM    
Vernacular Title:
Zyklophosphamid in der Behandlung der Immunhämozytopenien
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MeSH Terms
Descriptor/Qualifier:
Anemia, Hemolytic, Autoimmune / drug therapy*
Complement C3 / analysis
Cyclophosphamide / therapeutic use*
Dose-Response Relationship, Drug
Humans
Immunosuppression
Prednisone / therapeutic use
Splenectomy
Thrombocytopenia / drug therapy*
Chemical
Reg. No./Substance:
0/Complement C3; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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