| Cyclic spermidine alkaloids and flavone glycosides from Meehania fargesii. | |
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MedLine Citation:
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PMID: 20460799 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dried whole plant of Meehania fargesii (H. LéV.) C. Y. WU is utilized as an antipyretic and antidote for poison in China. Water soluble fractions, obtained from an 80% acetone extract of the whole plant, showed hyaluronidase inhibitory activity. From these fractions, hyaluronidase inhibitors were isolated along with two new spermidine alkaloids (meefarnines A and B), four new flavone glycosides (fargenins A-D), and 10 known compounds. The structure of each was elucidated by spectroscopic methods. |
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Authors:
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Toshihiro Murata; Toshio Miyase; Fumihiko Yoshizaki |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chemical & pharmaceutical bulletin Volume: 58 ISSN: 1347-5223 ISO Abbreviation: Chem. Pharm. Bull. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-12 Completed Date: 2010-09-01 Revised Date: 2011-03-08 |
Medline Journal Info:
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Nlm Unique ID: 0377775 Medline TA: Chem Pharm Bull (Tokyo) Country: Japan |
Other Details:
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Languages: eng Pagination: 696-702 Citation Subset: IM |
Affiliation:
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Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. murata-t@tohoku-pharm.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alkaloids
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chemistry*,
pharmacology Enzyme Inhibitors / chemistry, pharmacology Flavones / chemistry*, pharmacology Glycosides / chemistry*, pharmacology Hyaluronoglucosaminidase / antagonists & inhibitors Lamiaceae / chemistry* Magnetic Resonance Spectroscopy Molecular Structure Plant Structures / chemistry* Solubility Spermidine / chemistry*, pharmacology Water / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Alkaloids; 0/Enzyme Inhibitors; 0/Flavones; 0/Glycosides; 124-20-9/Spermidine; 7732-18-5/Water; EC 3.2.1.35/Hyaluronoglucosaminidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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