Document Detail

Cyclic leukocytosis and long survival in chronic myeloid leukemia.
MedLine Citation:
PMID:  6404119     Owner:  NLM     Status:  MEDLINE    
A patient with an unusually prolonged course of Ph' positive chronic myeloid leukemia is presented. His disease was marked by cyclic leukocytosis, various chromosomal aberrations and secondary thrombasthenia. In vitro culture studies and granulocyte-macrophage colony stimulating factor (GM-CSF) production were consistent with responsiveness of the leukemic clone to GM-CSF. The possible relationship between the long survival and the feedback regulation of leukopoiesis is raised.
A Inbal; E Akstein; I Barak; D Meytes; A Many
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta haematologica     Volume:  69     ISSN:  0001-5792     ISO Abbreviation:  Acta Haematol.     Publication Date:  1983  
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  353-7     Citation Subset:  IM    
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MeSH Terms
Blood Platelets / physiology
Chromosome Aberrations
Leukemia, Myeloid, Acute / complications*
Leukocytosis / complications*,  genetics
Middle Aged

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