Document Detail


Cyclic Cushing's disease associated with primary empty sella.
MedLine Citation:
PMID:  10854825     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A small number of cases of Cushing's disease (CD) associated with primary empty sella (ES) have been described in the literature. Pituitary microsurgery is the recommended treatment. An alternative is chronic treatment with ketoconazole, an inhibitor of adrenal cortisol synthesis. Cyclic Cushing's syndrome is characterized by episodic cortisol hypersecretion. CD is the most frequent etiology of cyclic Cushing's syndrome. To our knowledge, cyclic CD has not previously been reported in association with primary ES. We describe a patient with cyclic CD associated with primary ES who was initially treated with ketoconazole and subsequently cured by transsphenoidal surgery.
Authors:
Calvo-Romero; Morales-Pérez; Díaz-Pérez
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  European journal of internal medicine     Volume:  11     ISSN:  1879-0828     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-06-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  168-170     Citation Subset:  -    
Affiliation:
Internal Medicine Service, Infanta Cristina Universitary Hospital, Badajoz, Spain
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