Document Detail

Cycle outcome can be predicted by the growth profile of untransferred cleavage-stage embryos.
MedLine Citation:
PMID:  18252058     Owner:  NLM     Status:  MEDLINE    
Excess embryos obtained from intracytoplasmic sperm injection cycles may be cultured and observed until day 5 if the couple receiving treatment do not want them to be cryopreserved. In order to investigate the correlation between blastocyst formation in extended culture and pregnancy outcome, 194 patients treated in two separate IVF units were examined retrospectively. The patients were separated into two groups: group 1 with at least one blastocyst formed in culture, and group 2 with no blastocyst formation. The pregnancy rates were 60.0% and 41.7% for groups 1 and 2, respectively. The pregnancy rate in group 1 was statistically significantly higher than in group 2 (P = 0.01). The results suggest that the developmental potential of embryos obtained from a single assisted reproduction treatment cycle may be similar and that blastocyst formation in vitro may help to predict the pregnancy outcome of that cycle.
S Yilmaz; P Kutlu; K Sofuoglu; N Delikara; A Kolankaya; A Arici
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  16     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-02-06     Completed Date:  2008-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  124-8     Citation Subset:  IM    
Istanbul Ferticenter ART Center, Istanbul, Turkey.
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MeSH Terms
Blastocyst / physiology
Cleavage Stage, Ovum / physiology*
Embryo Transfer
Fertilization in Vitro*
Predictive Value of Tests
Pregnancy Outcome*
Retrospective Studies
Sperm Injections, Intracytoplasmic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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