Document Detail

Cycle characteristics of day 3 embryo transfers with 4-cell embryos only.
MedLine Citation:
PMID:  14531645     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Patient and cycle characteristics of day 3 transfers with developmentally lagging 4-cell embryos only were analyzed and related to the outcome of a live birth.
METHODS: Day 3 transfers with either 4-cell embryos only (study group; n = 138) or 8-cell embryos only (control group; n = 282) were compared retrospectively.
RESULTS: The total dose of FSH per treatment was higher, while the number of oocytes, zygotes, and transferred embryos was lower in the study group cycles compared to controls. The implantation, pregnancy, and live birth rates were dramatically lower in the study group compared to the control group. In the study group, the few cycles resulting in a live birth were characterized by a normal ovarian response to stimulation, similar to that of control group cycles with- or without a live birth.
CONCLUSIONS: In cycles characterized by intensive ovarian stimulation, but poor response, the chance for a live birth is extremely low after day 3 transfer of 4-cell embryos.
G Ertzeid; R Storeng; T Tanbo; P O Dale; S Bjercke; T Abyholm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  20     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-10-08     Completed Date:  2004-06-01     Revised Date:  2013-03-26    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  352-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Rikshospitalet University Hospital, 0027 Oslo, Norway.
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MeSH Terms
Birth Rate
Case-Control Studies
Embryo Implantation
Embryo Transfer*
Embryo, Mammalian / cytology,  physiology*
Fertilization in Vitro
Follicle Stimulating Hormone / administration & dosage
Ovulation Induction
Pregnancy Outcome
Retrospective Studies
Time Factors
Reg. No./Substance:
9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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