Document Detail


Cyanosis and congenital methemoglobinemia in a puppy.
MedLine Citation:
PMID:  9934925     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A six-month-old Pomeranian was referred for evaluation of cyanosis. The puppy had been cyanotic since it was acquired at six weeks of age, but otherwise appeared normal. Diagnostics were aimed at the most common causes (i.e., congenital defects in the cardiovascular and respiratory systems) of cyanosis in a juvenile animal. No clinically significant abnormalities were detected on evaluation of thoracic radiographs, echocardiogram, cardiac color-flow Doppler examination, or blood gases. At this point, a dysfunction in hemoglobin was considered as a possibility. Methemoglobinemia due to deficiency of methemoglobin reductase enzyme was diagnosed based on a specific assay.
Authors:
D M Fine; G E Eyster; L K Anderson; A Smitley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  35     ISSN:  0587-2871     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:    1999 Jan-Feb
Date Detail:
Created Date:  1999-11-01     Completed Date:  1999-11-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  33-5     Citation Subset:  IM    
Affiliation:
Department of Small Animal Clinical Sciences, Veterinary Teaching Hospital, Michigan State University, East Lansing 48824-1314, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cyanosis / congenital,  etiology,  veterinary*
Cytochrome-B(5) Reductase / blood,  deficiency
Diagnosis, Differential
Dog Diseases / congenital,  diagnosis*,  etiology
Dogs
Male
Methemoglobinemia / complications,  congenital,  diagnosis,  veterinary*
Chemical
Reg. No./Substance:
EC 1.6.2.2/Cytochrome-B(5) Reductase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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