| Cyanoacrylate Adhesive for the Closure of Truncal Veins: 60-Day Swine Model Results. | |
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MedLine Citation:
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PMID: 21757495 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: The introduction of cyanoacrylate (CA) within a blood vessel triggers polymerization, followed by an inflammatory reaction. Methods: A sheath was positioned 2.0 cm caudad to the junction of the superficial epigastric and abdominus rectus veins in 2 swine, followed by ultrasound-guided injection of 0.16 mL of CA glue. After glue delivery, the catheter was pulled back 3 cm, compression was applied to the treatment site, and the process was repeated for the entire length. At 60 days postimplantation, the veins were harvested surgically and examined histologically. Results: The histologic changes were consistent with a chronic foreign-body-type inflammatory response. Venous closure, segmental wall thickening, and fibrosis were observed. Conclusion: Injection of CA is feasible for closure of superficial veins in animal models. Vein closure is achieved via an inflammatory process which ultimately leads to fibrosis. |
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Authors:
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Jose I Almeida; Robert J Min; Rod Raabe; D J McLean; Monte Madsen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-14 |
Journal Detail:
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Title: Vascular and endovascular surgery Volume: - ISSN: 1938-9116 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136421 Medline TA: Vasc Endovascular Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Miami Vein Center, Miami, FL, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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