| Cutaneous toxoplasmosis in two dogs. | |
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MedLine Citation:
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PMID: 22529142 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cutaneous toxoplasmosis has been previously reported in human beings, rarely reported in cats, and reported in 1 dog with systemic toxoplasmosis. The present report describes 2 cases of cutaneous toxoplasmosis in 2 dogs treated with immunosuppressive therapy. One of the dogs developed generalized cutaneous pustules and pruritus, and the other dog only had a single subcutaneous nodule. Microscopically, skin biopsies showed moderate to severe pyogranulomatous and necrotizing dermatitis and panniculitis, with multifocal vasculitis and vascular thrombosis. Single or aggregates of protozoal tachyzoites were mostly intracytoplasmic and occasionally extracellular. The etiology was confirmed in both cases by immunohistochemistry and by polymerase chain reaction assays, which were followed by nucleic acid sequencing. Both patients were treated with clindamycin. The dog with generalized lesions developed pulmonary and neurological signs and was euthanized. The dog with a single nodule recovered completely with no remission of cutaneous lesions. |
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Authors:
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Aline Rodrigues Hoffmann; Jennifer Cadieu; Matti Kiupel; Ailam Lim; Steve R Bolin; Joanne Mansell |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Volume: 24 ISSN: 1943-4936 ISO Abbreviation: J. Vet. Diagn. Invest. Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9011490 Medline TA: J Vet Diagn Invest Country: United States |
Other Details:
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Languages: eng Pagination: 636-40 Citation Subset: IM |
Affiliation:
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1Aline Rodrigues Hoffmann, Department of Veterinary Pathobiology, College of Veterinary Medicine, MS4467 Texas A&M University, College Station, TX 77843. arodrigues@cvm.tamu.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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