| Cutaneous sensitivity to atracurium and vecuronium in patients suffering anaphylactoid reactions to neuromuscular blockers. | |
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MedLine Citation:
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PMID: 2864882 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using an ordinal measure of cutaneous sensitivity to intradermal injections of atracurium and vecuronium, 40 nonreacting subjects were compared with a group of 24 patients previously suffering life-threatening anaphylactoid reactions to other muscle relaxants. Enhanced cutaneous sensitivity to vecuronium was found in three, and to atracurium in two of the previously reacting group. With the exception of those showing abnormal reactivity, no significant difference was found in the distribution of cutaneous sensitivity in the control and reacting group. A concentration of vecuronium 8.75 times that of atracurium was required to produce an equivalent intradermal wheal response. |
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Authors:
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D C Galletly; B C Treuren |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Anaesthesia and intensive care Volume: 13 ISSN: 0310-057X ISO Abbreviation: Anaesth Intensive Care Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1985-11-20 Completed Date: 1985-11-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0342017 Medline TA: Anaesth Intensive Care Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 305-10 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anaphylaxis
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chemically induced,
prevention & control* Atracurium Drug Hypersensitivity / diagnosis* Humans Intradermal Tests* Isoquinolines / adverse effects* Neuromuscular Blocking Agents / adverse effects* Pancuronium / adverse effects, analogs & derivatives* Skin Tests* Vecuronium Bromide |
| Chemical | |
Reg. No./Substance:
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0/Isoquinolines; 0/Neuromuscular Blocking Agents; 0/Pancuronium; 50700-72-6/Vecuronium Bromide; 64228-79-1/Atracurium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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