Document Detail


Cutaneous sarcoidosis with cardiac involvement.
MedLine Citation:
PMID:  10491505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Despite the clinical importance of cardiac involvement in the prognosis of sarcoidosis, it is often overlooked because of the subclinical disease progression and difficulty in diagnosis. We report here five patients with cutaneous sarcoidosis lesions where cardiac involvement was detected with the appearance of mild cardiac symptoms on a careful examination of the heart after cutaneous sarcoidosis was diagnosed. In four of the five cases, the patients had annular lesions while the fifth case showed a nodular eruption on the face. Three of the five patients showed complete AV block while one showed complete right bundle block and left bundle anterior branch block. All four patients with conduction disturbances underwent a permanent pacemaker implantation with prednisolone tapering therapy. The remaining patient had congestive heart failure and was treated with prednisolone alone. The present findings support the belief that sarcoidosis patients with cutaneous lesions, especially facial annular lesions, should be carefully examined and monitored for cardiac involvement, even in cases without apparent cardiac symptoms.
Authors:
H Okamoto; K Mizuno; E Ohtoshi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of dermatology : EJD     Volume:  9     ISSN:  1167-1122     ISO Abbreviation:  Eur J Dermatol     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-12-16     Completed Date:  1999-12-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9206420     Medline TA:  Eur J Dermatol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  466-9     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Faculty of Medicine, Kyoto University, Kyoto 606-0813, Japan. hokamoto@takii.kmu.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Bundle-Branch Block / complications*,  diagnosis,  drug therapy
Echocardiography
Electrocardiography
Female
Heart Block / complications*,  diagnosis,  drug therapy
Humans
Male
Middle Aged
Pacemaker, Artificial
Prednisolone / administration & dosage
Prognosis
Sarcoidosis / complications*,  drug therapy,  pathology
Skin Diseases / complications*,  drug therapy,  pathology
Chemical
Reg. No./Substance:
50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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