| Cutaneous, pulmonary and sinusal aspergillosis in a diabetic patient. | |
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MedLine Citation:
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PMID: 20582892 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Cutaneous aspergillosis is rarely reported in diabetic patients. AIM: The objective of our study is to report a case of lethal disseminated aspergillosis revealed by multiples skin necroses, with pulmonary and sinusal involvement in a diabetic patient. CASE REPORT: A 60-year-old diabetic woman, presented with one month -rapidly -extensive, 1 to 10 cm skin necroses of the trunk, limbs and eyelids. Few days after her admission, she developed dyspnoea. Chest X-ray showed an interstitial and alveolar syndrome with multiple excavated anfractuous-edged-opacities. Facial CT scan showed a right orbital cellulitis with Pansinusitis. The methaminesilver stains on a cutaneous biopsy showed filamentous septate fungal hyphae with branches at right angles. The immunofluorescence with an anti-aspergillus serum was positive. The diagnosis of secondary disseminated aspergillosis to a primary pulmonary focus with cutaneous, sinusal, and upper airway's dissemination was made. The patient died despite an intravenous amphotericin B therapy. CONCLUSION: This report emphasizes the importance of evoking and seeking for a mycosis in every skin necrotic and ulcerative lesions occurring in an immunocompromised patient. The prognosis depends on the diagnosis and treatment institution delay. |
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Authors:
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Aida Khaled; Becima Fazaa; Donia Ammar; Alya Bouzgarrou; Samir Boubaker; Mohamed Ridha Kamoun |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: La Tunisie médicale Volume: 88 ISSN: 0041-4131 ISO Abbreviation: Tunis Med Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-28 Completed Date: 2010-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0413766 Medline TA: Tunis Med Country: Tunisia |
Other Details:
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Languages: eng Pagination: 519-22 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aspergillosis
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diagnosis* Dermatomycoses / diagnosis* Diabetes Complications / diagnosis*, microbiology* Fatal Outcome Female Humans Middle Aged Pulmonary Aspergillosis / diagnosis* Sinusitis / diagnosis*, microbiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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