Document Detail

Cutaneous polyarteritis nodosa in a child with positive antiphospholipid and P-ANCA.
MedLine Citation:
PMID:  8610225     Owner:  NLM     Status:  MEDLINE    
A case of juvenile cutaneous polyarteritis nodosa (cutaneous PAN) is presented. Since early infancy the child underwent attacks of fever and cutaneous rash that occasionally progressed to gangrene and amputations of distal portions of toes and fingers. Although occasional episodes of high blood pressure and persistence of moderate eosinophilia were present, the clinical pattern was mostly restricted to the musculoskeletal system and skin. The authors discuss the definition of the disease and its present therapeutic possibilities, calling attention to a feature not referred in previous reports: the unique co-existence of cutaneous PAN plus antiphospholipid antibodies (aPL) and perinuclear antineutrophil cytoplasmic antibodies (p-ANCA).
B A Pereira; N A Silva; A C Ximenes; S L Alvarenga; V S Barbosa
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  24     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  1995  
Date Detail:
Created Date:  1996-05-24     Completed Date:  1996-05-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  386-8     Citation Subset:  IM    
Department of Internal Medicine/Rheumatology Unit, Hospital das Clínicas, Faculty of Medicine, Federal University of Goiás (HC-FMUFG), Brazil.
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MeSH Terms
Antibodies, Antineutrophil Cytoplasmic
Antibodies, Antiphospholipid / blood*
Autoantibodies / blood*
Polyarteritis Nodosa / blood,  complications,  immunology*
Reg. No./Substance:
0/Antibodies, Antineutrophil Cytoplasmic; 0/Antibodies, Antiphospholipid; 0/Autoantibodies

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