Document Detail

Cutaneous and pericardial extramedullary hematopoiesis with cardiac tamponade in chronic myeloid leukemia.
MedLine Citation:
PMID:  3282429     Owner:  NLM     Status:  MEDLINE    
A 48-year-old woman with Philadelphia chromosome-positive chronic myeloid leukemia developed skin and pericardial extramedullary hematopoiesis. The echocardiogram revealed massive pericardial effusion with signs of tamponade. The cytocentrifuge preparation of pericardial fluid demonstrated all three hematopoietic components. Assays for the granulocyte-macrophage progenitor cells and erythroid progenitors on her pericardial fluid gave rise to colony numbers comparable to those of normal bone marrow cells. The patient was successfully treated with pericardiocentesis followed by short-term indwelling catheter drainage and administration of hydroxy-urea. There was no reaccumulation of fluid at ten months.
L Y Shih; F C Lin; T T Kuo
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  89     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-05-23     Completed Date:  1988-05-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  693-7     Citation Subset:  AIM; IM    
Department of Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
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MeSH Terms
Cardiac Tamponade / etiology*
Colony-Forming Units Assay
Hematopoiesis, Extramedullary*
Hematopoietic Stem Cells
Leukemia, Myeloid / complications*,  physiopathology
Middle Aged
Pericardial Effusion
Pericardium / physiopathology*
Skin / physiopathology*

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