Document Detail

Cutaneous nonpulmonary Mycobacterium chelonei infection. Successful treatment with sulfonamides in an immunosuppressed patient.
MedLine Citation:
PMID:  6380417     Owner:  NLM     Status:  MEDLINE    
A 52-year-old man, who had received immunosuppressive therapy for four years after renal transplantation, had a deep-set skin infection in his thigh caused by Mycobacterium chelonei. In vitro studies indicated that the organism was resistant to antimycobacterial agents but potentially sensitive to high-dose sulfonamide therapy. Repeated surgical excisions failed to eradicate the infection, as documented by histopathologic examination. The combination of a reduced dose of immunosuppressive medication and the administration of high-dose sulfonamide therapy resulted in clinical recovery.
J D Heironimus; R E Winn; C B Collins
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  120     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-08-30     Completed Date:  1984-08-30     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1061-3     Citation Subset:  AIM; IM    
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MeSH Terms
Drug Combinations / therapeutic use
Drug Therapy, Combination
Immunosuppressive Agents / adverse effects
Kidney Failure, Chronic / surgery
Kidney Transplantation
Middle Aged
Mycobacterium Infections / drug therapy*
Skin Diseases, Infectious / drug therapy*
Sulfadiazine / therapeutic use*
Sulfamerazine / therapeutic use*
Sulfamethazine / therapeutic use*
Reg. No./Substance:
0/Drug Combinations; 0/Immunosuppressive Agents; 127-79-7/Sulfamerazine; 57-68-1/Sulfamethazine; 68-35-9/Sulfadiazine; 8017-57-0/trisulfapyrimidine

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