| Cutaneous neuroblastoma-like schwannoma: a report of two cases, one with a plexiform pattern, and a review of the literature. | |
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MedLine Citation:
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PMID: 19922484 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cutaneous schwannomas in their classical form are readily identified histologically. A number of variants, including ancient, cellular, epithelioid, plexiform, microcystic and neuroblastoma-like, may cause diagnostic difficulty and rarely be confused with malignancy. Neuroblastoma-like schwannoma was first described by Goldblum et al. in 1994, and very few cases have since been reported. It is a benign sporadic neoplasm with no reported association with neurofibromatosis, and is characterized histologically by small round lesional cells surrounding collagenous cores forming rosette-like structures. The differential diagnosis includes other lesions with the formation of rosettes including neuroblastoma, low-grade fibromyxoid sarcoma and dendritic cell neurofibroma, as well as primitive neuroectodermal tumors and rare malignant transformation in a schwannoma. We describe two further cases of this rare entity and review the literature on the subject. Our first case additionally has a plexiform multinodular pattern, a feature described in only one previous report. |
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Authors:
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Ravi Suchak; Bostjan Luzar; Carlos E Bacchi; Brigid Maguire; Eduardo Calonje |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2009-11-17 |
Journal Detail:
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Title: Journal of cutaneous pathology Volume: 37 ISSN: 1600-0560 ISO Abbreviation: J. Cutan. Pathol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-10-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0425124 Medline TA: J Cutan Pathol Country: Denmark |
Other Details:
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Languages: eng Pagination: 997-1001 Citation Subset: IM |
Affiliation:
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Department of Dermatopathology, St John's Institute of Dermatology, St Thomas's Hospital, Lambeth Palace Road, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Neurilemmoma / metabolism, pathology*, surgery Neuroblastoma / metabolism, pathology* Skin Neoplasms / metabolism, pathology*, surgery Treatment Outcome Tumor Markers, Biological / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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