Document Detail

Cutaneous melanoma-associated retinopathy.
MedLine Citation:
PMID:  7800366     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To define further the syndrome of cutaneous melanoma-associated retinopathy, of which only five affected patients have been reported previously. METHODS: Three men with melanoma-associated retinopathy were examined and studied electrophysiologically. Two were studied in detail psychophysically. RESULTS: Visual symptoms consisted of flickering black and white spots, shimmering patches of colors, and night blindness. The onset was acute and nonprogressive. Reduced amplitudes were observed in the flash electroretinographic b-wave and the pattern electroretinogram. Color vision, contrast sensitivity, and light- and dark-adapted perimetric sensitivities were abnormal. In one patient, the rate of dark adaptation was normal with elevated final cone and rod thresholds. CONCLUSIONS: Melanoma-associated retinopathy is a paraneoplastic syndrome distinct from cancer-associated retinopathy with a different visual prognosis. It may preferentially affect men.
R Y Kim; S Retsas; F W Fitzke; G B Arden; A C Bird
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ophthalmology     Volume:  101     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-01-23     Completed Date:  1995-01-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1837-43     Citation Subset:  IM    
Institute of Ophthalmology and Moorfields Eye Hospital, London, UK.
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MeSH Terms
Color Vision Defects / etiology
Dark Adaptation
Melanoma / complications*
Middle Aged
Paraneoplastic Syndromes*
Retinal Diseases / diagnosis,  etiology*
Skin Neoplasms / complications*
Vision Disorders / diagnosis,  etiology
Vision Tests
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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