Document Detail

Cutaneous manifestations in brucellosis: a prospective study.
MedLine Citation:
PMID:  17901020     Owner:  NLM     Status:  MEDLINE    
Brucellosis remains an important public health problem in Turkey, just as it is in other regions of the world. This study was conducted to determine the types and rates of cutaneous lesions that occur in patients with brucellosis. Brucellosis was diagnosed by standard tube agglutination testing for Brucella antibodies at a titer of 1/160 or higher in the presence of compatible clinical findings. A total of 140 patients who had been given a diagnosis of brucellosis were prospectively observed in the dermatology clinic. Of these patients, 102 (72.9%) were female, with a mean age of 44.11+/-18.22 y, and 38 (27.1%) were male, with a mean age of 46.44+/-14.58 y. The duration of symptoms was less than 2 mo (acute) in 75 patients (53.5%), from 2 to 12 mo (subacute) in 30 patients (21.4%), and longer than 12 mo (chronic) in 35 patients (25.0%). Cutaneous findings related to brucellosis were observed in 8 (5.71%) of the 140 cases. Maculopapular eruptions were observed in 2 patients (25%), erythema nodosum-like lesions in 2 (25%), psoriasiform lesions in 1 (12.5%), palmar erythema in 1 (12.5%), malar eruption in 1 (12.5%), and palmar eczema in 1 (12.5%). The investigators concluded that although cutaneous findings encountered in brucellosis are generally not specific to this disease, the presence of these findings may be useful in diagnosing brucellosis in persons who live in, or used to live in, endemic regions.
Cenk Akcali; Lutfu Savas; Mete Baba; Tuba Turunc; Deniz Seckin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in therapy     Volume:  24     ISSN:  0741-238X     ISO Abbreviation:  Adv Ther     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-09-28     Completed Date:  2008-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8611864     Medline TA:  Adv Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  706-11     Citation Subset:  T    
Department of Dermatology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.
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MeSH Terms
Acute Disease
Brucellosis / pathology*
Chronic Disease
Middle Aged
Prospective Studies
Skin / pathology*
Skin Diseases / epidemiology,  pathology*

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