| Cutaneous hypersensitivity to co-trimoxazole after autologus bone marrow transplantation and immunotherapy with interferon alpha-2A and interleukin-2. | |
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MedLine Citation:
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PMID: 8270579 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Typical cutaneous hypersensitivity reaction to co-trimoxazole was seen in a woman after autologous bone marrow transplantation and immunotherapy. She had developed no such reaction during chemotherapy prior to the transplant or immediately after the transplant. The immunoperturbed state that exists for a period of time after bone marrow transplantation, especially in the presence of immunomodulation caused by combined therapy with recombinant human interferon alpha and interleukin-2, with exposure to potentially reaginic agents may have contributed to the development of the hypersensitivity reaction in this patient. |
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Authors:
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J Mehta; A Nagler; A Ackerstein; J Kapelushnik; R Or |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of the Association of Physicians of India Volume: 41 ISSN: 0004-5772 ISO Abbreviation: J Assoc Physicians India Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1994-02-02 Completed Date: 1994-02-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7505585 Medline TA: J Assoc Physicians India Country: INDIA |
Other Details:
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Languages: eng Pagination: 235-6 Citation Subset: IM |
Affiliation:
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Department of Bone Marrow Transplantation, Hadassah University Hospital, Jerusalem, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bone Marrow Transplantation* Drug Hypersensitivity Female Humans Interferon-alpha / therapeutic use Interleukin-2 / therapeutic use Skin / drug effects, immunology Trimethoprim-Sulfamethoxazole Combination / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Interferon-alpha; 0/Interleukin-2; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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