Document Detail

Cutaneous granulomatous vasculitis associated with chronic lymphocytic leukemia: case report and review of literature of a rare entity.
MedLine Citation:
PMID:  22483523     Owner:  NLM     Status:  MEDLINE    
Cutaneous granulomatous vasculitis associated with lymphoproliferative disorders is a rare entity, with only 14 cases previously reported in the English literature. Patients generally present with nodules or ulcers involving the extremities, which can appear months or years before or after onset of systemic disease. Granulomatous vasculitis has a poor prognosis when associated with underlying lymphoproliferative disorders, with the majority of reported cases fatal. Knowledge of this unusual entity is important to allow for proper clinical evaluation, follow-up, and therapy. We report a 77-year-old female with chronic lymphocytic leukemia and granulomatous vasculitis, which highlights the features of this association, and expands the clinical data.
Erich M Gaertner; Stephen A Switlyk
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-03-15
Journal Detail:
Title:  Dermatology online journal     Volume:  18     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-04-09     Completed Date:  2012-08-03     Revised Date:  2012-10-04    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  12     Citation Subset:  IM    
SaraPath Diagnostics, Sarasota, Florida, USA.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Antineoplastic Agents / therapeutic use
Erythrocyte Transfusion
Leukemia, Lymphocytic, Chronic, B-Cell / complications,  drug therapy
Nitrogen Mustard Compounds / therapeutic use
Paraneoplastic Syndromes / diagnosis*,  drug therapy,  pathology
Prednisone / therapeutic use
Skin Diseases, Vascular / diagnosis*,  drug therapy,  pathology
Treatment Outcome
Vasculitis / diagnosis*,  drug therapy,  etiology,  pathology
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antineoplastic Agents; 0/Nitrogen Mustard Compounds; 16506-27-7/bendamustine; 53-03-2/Prednisone

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