Document Detail


Cutaneous fixed drug eruption to fluconazole.
MedLine Citation:
PMID:  20684158     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fixed drug eruption (FDE) is an uncommon medication-induced cutaneous reaction. A case of fluconazole-induced FDE is described. A 64-year-old woman presented with eight ovoid hyperpigmented patches on the arms, palm and lower leg that had recurred multiple times at the identical sites at seemingly random intervals over the prior six months. The clinicopathologic diagnosis strongly favored FDE, though the culprit medication remained elusive. Further evaluation and oral rechallenge confirmed the diagnosis of FDE to fluconazole. The patient had not related the eruption to this medication due to the short courses of therapy and prior use without incident. FDE to fluconazole has only been rarely reported in the literature. The presentation and evaluation of FDE is reviewed.
Authors:
Hobart W Walling; Brian L Swick
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  9     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-05     Completed Date:  2010-08-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1025-8     Citation Subset:  IM    
Affiliation:
University of Iowa, Department of Dermatology, Iowa City, IA, USA. hobartwalling@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Antifungal Agents / administration & dosage,  adverse effects*
Drug Eruptions / diagnosis,  etiology*
Female
Fluconazole / administration & dosage,  adverse effects*
Humans
Middle Aged
Chemical
Reg. No./Substance:
0/Antifungal Agents; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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