| Cutaneous disseminated xanthogranuloma in an adult: case report and review of the literature. | |
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MedLine Citation:
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PMID: 19537282 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Xanthogranuloma (XG) is a rare, non-Langerhans cell histiocytosis (LCH) that most commonly presents in infancy or early childhood. The condition is typified by the formation of reddish to yellow papules and nodules that are usually solitary. Xanthogranuloma rarely occurs in adults with immunohistochemical features similar to those seen in juvenile XG. Lesions in the adult form seen in juvenile XG. Lesions in the adult form also are typically solitary. We describe a 70-year-old white man who presented with widespread flat-topped, reddish to yellow papules and nodules with histologic and immunohistochemical findings consistent with XG. We explore the pathogenesis, differential diagnosis, prognosis, and treatment of this rare eruption. Comparison of adult and juvenile XG will facilitate a better understanding of the disease. Although rare, XG is an important disease to consider in the differential diagnosis of xanthomatous disease in adults. |
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Authors:
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Adam Asarch; Jens J Thiele; Harty Ashby-Richardson; Pamela S Norden |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Cutis; cutaneous medicine for the practitioner Volume: 83 ISSN: 0011-4162 ISO Abbreviation: Cutis Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-06-19 Completed Date: 2009-08-04 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0006440 Medline TA: Cutis Country: United States |
Other Details:
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Languages: eng Pagination: 243-9 Citation Subset: IM |
Affiliation:
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Tufts University School of Medicine, Boston, Massachusetts, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Diagnosis, Differential Humans Male Xanthogranuloma, Juvenile / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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