Document Detail

Cutaneous adiaspiromycosis: a distinct dermatologic entity associated with Chrysosporium species.
MedLine Citation:
PMID:  15577766     Owner:  NLM     Status:  MEDLINE    
Primary cutaneous infection with Chrysosporium, a saprophytic fungus commonly found in soil, is believed to be very rare, with only two previously reported cases. We present a case of localized cutaneous Chrysosporium in an immunocompromised heart transplant patient. Considering that the histology of the skin in this case is superimposable on that seen in pulmonary Chrysosporium known as adiaspiromycosis, we regard the cutaneous variant in the absence of pulmonary disease as a distinct dermatologic entity. The low frequency of reports of primary cutaneous Chrysosporium infection suggests either underreporting of this diagnosis in the literature, or misidentification of this fungus as another more common mycotic species sharing morphologic similarities. By amplifying our understanding of Chrysosporium infection in the skin, this disorder will be easier to identify and treat.
William G Stebbins; Anna Krishtul; Edward J Bottone; Robert Phelps; Steven Cohen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  51     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-03     Completed Date:  2005-03-25     Revised Date:  2005-06-24    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S185-9     Citation Subset:  IM    
Department of Dermatology, Mount Sinai Hospital and School of Medicine, New York, New York 10029, USA.
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MeSH Terms
Antifungal Agents / therapeutic use
Dermatomycoses / diagnosis*,  drug therapy,  pathology
Drug Therapy, Combination
Fluconazole / therapeutic use
Heart Transplantation / immunology*
Immunocompromised Host*
Pyridones / therapeutic use
Reg. No./Substance:
0/Antifungal Agents; 0/Pyridones; 29342-05-0/ciclopirox; 86386-73-4/Fluconazole
Erratum In:
J Am Acad Dermatol. 2004 Dec;51(6):1040

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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