Document Detail


Cutaneous infectious granuloma caused by Phenylobacterium in an adult with myelodysplastic syndrome: a first case report.
MedLine Citation:
PMID:  20394459     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Painful granulomatous lesions appeared on the face of a 36-year-old man with myelodysplastic syndrome. Skin biopsy revealed chronic inflammatory granuloma. Bacterial cultures of the lesions and blood indicated the same unknown Gram-negative rod bacterium. The 16S ribosomal RNA sequence of the unknown bacterium yielded Phenylobacterium. Thus, we diagnosed cutaneous infectious granuloma caused by Phenylobacterium and myelodysplastic syndrome/refractory cytopenia with multi-lineage dysplasia. After treatment with combined antibacterials that were selected based on the tests for drug sensitivity, the lesions disappeared with only scars remaining and without any signs of relapse after 1 year. This is the first case report of cutaneous infectious granuloma caused by Phenylobacterium.
Authors:
Xiao-hua Zhu; Feng Li; Jin-hua Xu; Lei-hong Xiang; Ke-fei Kang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of clinical dermatology     Volume:  11     ISSN:  1175-0561     ISO Abbreviation:  Am J Clin Dermatol     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-20     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100895290     Medline TA:  Am J Clin Dermatol     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  363-6     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Face
Gram-Negative Bacterial Infections / complications*,  diagnosis
Granuloma / complications*,  microbiology*
Humans
Male
Myelodysplastic Syndromes / complications*
Opportunistic Infections / complications*,  diagnosis,  microbiology
Proteobacteria / genetics,  isolation & purification*
Skin Diseases / complications*,  microbiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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