Document Detail


Cushing's syndrome of nonpituitary causes.
MedLine Citation:
PMID:  19491665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Cushing's syndrome is being recognized with greater frequency and in patients with milder disease. Many of these individuals have nonpituitary causes of their hypercortisolism. This review discusses the classification, presentation, diagnosis, and therapy of patients with Cushing's syndrome from nonpituitary causes. RECENT FINDINGS: Many previously unrecognized or poorly understood causes of Cushing's syndrome have been elucidated. It is now appreciated that essentially any form of exogenous glucocorticoid is capable of causing Cushing's syndrome. Additionally, new findings have led to a more complete understanding of bilateral nodular adrenal disease. SUMMARY: The diagnosis of patients with less profound cortisol excess has increased the prevalence of Cushing's syndrome and made nonpituitary causes more common. As a result, clinicians must be cognizant of such patients and pursue the diagnosis when appropriate.
Authors:
Ty B Carroll; James W Findling
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in endocrinology, diabetes, and obesity     Volume:  16     ISSN:  1752-2978     ISO Abbreviation:  Curr Opin Endocrinol Diabetes Obes     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-06-30     Completed Date:  2009-10-22     Revised Date:  2010-09-01    
Medline Journal Info:
Nlm Unique ID:  101308636     Medline TA:  Curr Opin Endocrinol Diabetes Obes     Country:  England    
Other Details:
Languages:  eng     Pagination:  308-15     Citation Subset:  IM    
Affiliation:
Endocrinology Center, Medical College of Wisconsin, W129 N7055 Northfield Drive, Building A, Suite 203, Menomonee Falls, WI 53051, USA. tcarroll@mcw.edu
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MeSH Terms
Descriptor/Qualifier:
Cushing Syndrome / diagnosis,  etiology*,  therapy
Glucocorticoids / metabolism
Humans
Hydrocortisone / metabolism
Chemical
Reg. No./Substance:
0/Glucocorticoids; 50-23-7/Hydrocortisone
Comments/Corrections
Erratum In:
Curr Opin Endocrinol Diabetes Obes. 2010 Oct;17(5):492

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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