| Cushing's syndrome and chronic venous ulceration - a clinical challenge. | |
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MedLine Citation:
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PMID: 21078130 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's syndrome, in whom long-term topical steroid therapy was used to treat varicose eczema, which contributed to the development of type 2 diabetes, morbid obesity, sleep apnoea and chronic wound sepsis. In this case, repeated hospital admissions and systemic antibiotics were associated with considerable comorbidity. Aggressive local treatment, consisting of potassium permanganate soaks and irrigating gels, was highly effective in reducing the amount of exudate, pain and preventing from further deterioration of the patient's legs. |
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Authors:
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Moushmi Biswas; Owain Gibby; Tzvetanka Ivanova-Stoilova; Keith Harding |
Publication Detail:
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Type: Journal Article Date: 2010-11-16 |
Journal Detail:
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Title: International wound journal Volume: 8 ISSN: 1742-481X ISO Abbreviation: Int Wound J Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230907 Medline TA: Int Wound J Country: England |
Other Details:
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Languages: eng Pagination: 99-102 Citation Subset: IM |
Copyright Information:
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© 2010 The Authors. © 2010 Blackwell Publishing Ltd and Medicalhelplines.com Inc. |
Affiliation:
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M Biswas, MRCP, Department of Diabetes, Royal Gwent Hospital, Newport, UK O Gibby, FRCP, Department of Diabetes, Royal Gwent Hospital, Newport, UK T Ivanova-Stoilova, MD, PhD, FRCA, FFP, MRCA, Department of Anaesthesia and Pain Medicine, Royal Gwent Hospital, Newport, UK K Harding, FRCS, Department of Wound Healing, Cardiff University, School of Medicine, Heath Park, Cardiff, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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