Document Detail

Cushing's disease associated with unruptured large internal carotid artery aneurysm. Case report.
MedLine Citation:
PMID:  20805651     Owner:  NLM     Status:  MEDLINE    
A 40-year-old woman with Cushing's disease presented with hypertensive cerebral hemorrhage. Neuroimaging detected an unruptured large intracavernous aneurysm, which projected beyond the midline, and thin crescent-shaped adenoma along the aneurysm wall. The aneurysm was treated with endovascular tight packing with coils. Transsphenoidal adenomectomy was then safely performed. The signs of Cushing's disease were resolved, and she was discharged without deficits. The first line therapy for Cushing's disease is transsphenoidal adenomectomy. However, the therapeutic strategy and optimal timing of treatment are unclear for Cushing's disease with large intracavernous aneurysm. The present case shows that transsphenoidal surgery was safely possible with minimal invasiveness after embolization of the intracavernous aneurysm.
Yasuo Nishijima; Yoshikazu Ogawa; Kenichi Sato; Yasushi Matsumoto; Teiji Tominaga
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurologia medico-chirurgica     Volume:  50     ISSN:  1349-8029     ISO Abbreviation:  Neurol. Med. Chir. (Tokyo)     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-31     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400775     Medline TA:  Neurol Med Chir (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  665-8     Citation Subset:  IM    
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi.
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MeSH Terms
Aneurysm / complications,  pathology*,  surgery
Carotid Artery Diseases / complications,  pathology*,  surgery
Cushing Syndrome / complications*
Embolization, Therapeutic / methods
Hemangioma, Cavernous, Central Nervous System / complications,  pathology,  surgery
Intracranial Hemorrhage, Hypertensive / complications,  pathology*,  surgery
Pituitary Neoplasms / complications*,  surgery
Sphenoid Bone / surgery
Surgical Procedures, Minimally Invasive / methods
Treatment Outcome
Vascular Surgical Procedures / methods

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