| Cushing syndrome in an infant due to cortisol secreting adrenal pheochromocytoma: a rare association. | |
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MedLine Citation:
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PMID: 20662337 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Adrenocortical tumors are the most common cause of endogenous Cushing syndrome in infancy and early childhood. Cushing syndrome resulting from ectopic adrenocorticotrophic hormone (ACTH) producing tumor has been infrequently reported in adults. Cortisol secreting pheochromocytoma is rarely reported in literature. We report an eleven month old child presenting to us as Cushing syndrome with hypertension due to left adrenal tumor. He was treated with antihypertensives and left adrenalectomy was done under perioperative glucocorticoid coverage. Diagnosis of pheochromocytoma was made only after histopathology. Despite the rare association of Cushing syndrome and pheochromocytoma, preoperative diagnosis of pheochromocytoma is required for appropriate perioperative medical and anaesthetic management to prevent life threatening complications. |
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Authors:
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Manish Kumar; Vishal Kumar; B Talukdar; Anup Mohta; Nita Khurana |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 23 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-28 Completed Date: 2010-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
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Languages: eng Pagination: 621-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics and Pediatric Surgery, Chacha Nehru Bal Chikitsalaya, Geeta Colony, India. manishkp75@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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blood,
complications* Adrenal Glands / metabolism, pathology Adrenalectomy Calcium / administration & dosage Combined Modality Therapy Cushing Syndrome / etiology*, pathology, therapy Enalapril / therapeutic use Humans Hydrocortisone / blood* Hypertension / blood, etiology, pathology Infant Male Pheochromocytoma / blood, complications* Prednisolone / therapeutic use Thyroxine / therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone; 50-24-8/Prednisolone; 7440-70-2/Calcium; 7488-70-2/Thyroxine; 75847-73-3/Enalapril |
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