Document Detail

Cushing syndrome as a presenting symptom of renal tumors in children.
MedLine Citation:
PMID:  19353619     Owner:  NLM     Status:  MEDLINE    
Cushing syndrome as the presenting symptom of a malignant renal tumor in children is rare. We report the first case of paraneoplastic Cushing syndrome due to a Wilms tumor, in which clinical and biological signs of hypercortisolism regressed during preoperative chemotherapy. Additionally, we reviewed the literature on paraneoplastic Cushing syndrome secondary to pediatric renal tumors.
H Segers; J C van der Heyden; E L T van den Akker; R R de Krijger; C M Zwaan; M M van den Heuvel-Eibrink
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  53     ISSN:  1545-5017     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-06-15     Completed Date:  2009-07-09     Revised Date:  2010-07-30    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  211-3     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
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MeSH Terms
Adrenocorticotropic Hormone / blood
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Child, Preschool
Combined Modality Therapy
Cushing Syndrome / etiology*
Hydrocortisone / blood
Kidney Neoplasms / complications*,  pathology,  therapy
Paraneoplastic Syndromes / etiology
Wilms Tumor / complications*,  pathology,  therapy
Reg. No./Substance:
50-23-7/Hydrocortisone; 9002-60-2/Adrenocorticotropic Hormone
Comment In:
Pediatr Blood Cancer. 2010 Sep;55(3):589-90   [PMID:  20658641 ]

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