Document Detail

Curve fitting for repeated measurements made at irregular time-points.
MedLine Citation:
PMID:  6518246     Owner:  NLM     Status:  MEDLINE    
In longitudinal studies of human populations, it is often not feasible to measure all subjects at the same time-points. This precludes the use of classical methods of curve fitting for repeated measurements. When the total interval of follow-up is short for all subjects in the study, an intraclass correlation matrix is assumed for the measurements on each subject. An estimation procedure based on iteratively reweighted least squares is described. The model is then generalized to incorporate covariables, with little modification in the estimation procedure. The proposed method is applied to data from a longitudinal study of bone mass in postmenopausal women.
S L Hui
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biometrics     Volume:  40     ISSN:  0006-341X     ISO Abbreviation:  Biometrics     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1985-03-19     Completed Date:  1985-03-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370625     Medline TA:  Biometrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  691-7     Citation Subset:  IM    
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MeSH Terms
Longitudinal Studies*
Middle Aged
Osteoporosis / epidemiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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